Downgrades Buy Neutral X

KPTI Karyopharm Therapeutics

H.C. Wainwright

Resumed Buy X

KPTI Karyopharm Therapeutics

H.C. Wainwright

$27

Initiated Overweight X

KPTI Karyopharm Therapeutics

Piper Sandler

$8

Upgrades Sec Perform Outperform X

KPTI Karyopharm Therapeutics

RBC Capital Mkts

$7 $10

Upgrades Underweight Neutral X

KPTI Karyopharm Therapeutics

JP Morgan

$8

Resumed Equal-Weight X

KPTI Karyopharm Therapeutics

Morgan Stanley

$27 $10

Upgrades Neutral Overweight X

KPTI Karyopharm Therapeutics

JP Morgan

$8 $16

Reiterated Buy X

KPTI Karyopharm Therapeutics

H.C. Wainwright

$29 $32

Reiterated Outperform X

KPTI Karyopharm Therapeutics

Robert W. Baird

$15 $25

Downgrades Overweight Neutral X

KPTI Karyopharm Therapeutics

JP Morgan

$21 $7

Reiterated Underperform X

KPTI Karyopharm Therapeutics

BofA/Merrill

$15 $5

Downgrades Neutral Underperform X

KPTI Karyopharm Therapeutics

BofA/Merrill

$15 $5

Upgrades Underperform Neutral X

KPTI Karyopharm Therapeutics

BofA/Merrill

Initiated Buy X

KPTI Karyopharm Therapeutics

B. Riley FBR

$23

Upgrades Neutral Outperform X

KPTI Karyopharm Therapeutics

Wedbush

$19

Downgrades Outperform Neutral X

KPTI Karyopharm Therapeutics

Wedbush

$20 $19

Resumed Outperform X

KPTI Karyopharm Therapeutics

Leerink Partners

$19

KPTI  Karyopharm Therapeutics Inc.

Karyopharm Therapeutics Inc. is a clinical-stage pharmaceutical company. The Company is focused on the discovery, development and commercialization of drugs directed against nuclear transport and related targets for the treatment of cancer and other diseases. It has discovered and is developing small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein, XPO1. The Company's lead drug candidate, selinexor (KPT-330), is an orally administered agent for the treatment of cancer indications with unmet clinical need, mainly hematologic malignancies. It is also engaged in the clinical development of selinexor in various solid tumor indications. Oral selinexor is being evaluated in multiple later-phase clinical trials in patients with relapsed and/or refractory hematological and solid tumor malignancies. Its lead drug candidate, oral selinexor (KPT-330), as well as verdinexor (KPT-335), KPT-8602 and KPT-9274 are in clinical development.